It seems like the only applications that most people still run locally on their desktop are Web browsers and Office suite programs, and Office is jeopardized by online versions. Meanwhile, a lot of attention is going to mobile apps, and there is a strong chance that mobile operating systems could eventually be running on devices powerful enough to replace desktop systems for typical usage.
Given all of these factors, I think it is quite possible that desktop applications will become a niche market, reserved for "workstation" style tasks like multimedia processing, number crunching, and development. What do you think?
Justin James is the Lead Architect for Conigent.