Do you use SnagIt? I have been using this software for years and I am very happy with it. With SnagIt, you have the ability to create profiles. The profile may allow you to capture an entire window, a region, a menu, etc.
Recently, TechSmith released a Flickr profile that allows you to capture a screen or portion thereof and have it upload to Flickr instantly. It is a great feature that really streamlines my work.
Let's see it in action.
When you first open SnagIt, you can choose the appropriate profile. I downloaded and installed the Flickr profiles off of their website. Let's go ahead and send a screenshot of my blog to Flickr using a SnagIt profile. Once you add the finishing touches on your screen capture, click Finish and a SnagIt to Flickr Output Options window appears.
Note: You must first authorize your browser to allow uploading to Flickr. A browser will open asking you to sign-in to Flickr to allow access. Once you allow access, you can continue authorization, set your options in SnagIt, and choose Upload.