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When Windows is first installed on a drive, it characterizes itself with the hardware associated with it and the BIOS settings. Taking that drive to another mach ine will not allow you to boot as the hardware and BIOS is not a match to what is on the drive. It might be possible to boot to the WinX disk in the new machine and the suspect drive. Attempt a repair but depending on you Win version, you may not be able to return it back to the original machine.