I'm quite surprised that Malware-Bytes wasn't included in the list of choices, being how many times I've heard of people use it. Oh wait, no, that's Spybot that I hear people use...
I previously used S&D, but it seemed to give more false positives while missing the true, egregious software--not to mention that my other protections saw some of S&Ds drivers and processes as spyware itself. That's funny.
Of course I do not infer that Spybot is spyware, that's silly, but just that there are superior products. Malware-bytes is one of them.
As always, the best security is a conscious user. Yeah, there are "Drive-by" infections and the like, but in the end, the user has to be cautious of where they click...
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