nope
We are a small company that requires extensive travel, so the last thing I want out of an interviewee is a knee-jerk "YES" when I ask them how they feel about 75% travel...
In an interview, I'm looking for a candidate's soft skills as much as the technical qualifications, since our people do lots of customer face-time and are often the only representative of our company our customer meets in person. I don't mind "naysaying" from an interviewee, if it's offered in a tactful way. Techies often make the mistake of thinking that it doesn't matter if they're a jerk because of their credentials. That might've been true 25 years ago, but it is no longer the case.