I've started simply removing the hard drive from the infected machine and using a USB-HDD adapter, connecting it to a machine that is known to be clean and is not on a network. Takes several scans of UnHackMe, ComboFix and Avast Pro, but I've successfully cleaned off the AvPro2010 from at least ten machines. Seems that once the rootkit hiding it is killed, the actual trojan comes off completely. Yet to have one come back to me with recurrence. Of course, you need to make sure that the AV software on the "clean" machine is solid, to prevent its infection. Normal cleanup can take over four hours, and this method usually works the problems out in under three.