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The company for which I work has thousands of backup appliances in the field from which we get a tremendous amount of data concerning this subject. After years using RAID-5, we now ship only RAID-1 in our low-end appliances, RAID-10 in our medium-end appliances, and RAID-6 (actually, RAID-1/RAID-6) in our higher-end appliances.

In the real world, with larger disks, the major reason that you end up going to RAID-6 over RAID-5 is the concern with respect to drive failure during in-operation rebuild.
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Mark Campbell
http://www.unitrends.com/