You can be constantly connected to your data, anywhere?
For the price of wireless data services, sure. But what if your company has some security sense and doesn't put all their business critical data up in the magical cloud? Then you'd have to have a constant VPN connection into your network, and that could prove to be a substantial security issue.

Edited:
I might add, on a note to the battery life, that even on my iPod, the battery life does decrease over time. If the life of an iPod (considerable less power hungry than an iPad) will shorten, what can we expect for the hungrier iPad?