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if the HIPs in Comodo Firewall Defense+, or Kaspersky, or even GDATA couldn't detect the file manipulating ways of any Zues variant.

I've used GDATA a little and it seems pretty wise to the ways of the Windows operating system(XP).

So far, all of them seem invulnerable to sabotage by the malware. Prevx is supposed to work while the system is infected with such malware.