I can think of nothing else that constricts the use of software in my organization more than an app, web page, etc. that is not accessible. The biggest problem here is software integration. The agency standard is Microsoft Windows, but no software upgrade is possible without it passing accessibility use by the version of JAWS that we are using. (Yes, we're two versions behind. There is a issue with the mirror driver in Windows XP working with the newer version of JAWS.) In our agency, IR is not the one to test for accessibility. It is actually done by a separate group in house that has HTML and accessibility tool skills, but that is the extent of their expertise.