1. Using a Mac within an Active Directory environment.
2. Using iPhone/iOS within secured VPN/network environments (particularly, the kinds of VPNs that don't just use PPTP or IPSEC for security).
3. Centralized software/patch management for Macs (or iOS devices).
Seeing these kinds of issues addressed would go a LONG way to showing systems and network administrators in "bigger than a workgroup" networks how they can integrate Macs into the mix without compromising security. I've never seen anyone address these issues from a "how to" perspective, and they are the kind of things that people who run business networks care about.
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