SuperAntiSpyware
We use MSE at my tech college and it is a total fail. They don't want to spend the money to use something good. There are always virus and malware on the computer that MSE failed to find. I can't recommend that program at all. I do believe they are up and coming and probably will take over but at this time, I haven't seen anything good.
SpyBot I don't use much any more. It's a little slow sometimes. Though I will still bring it out if I have too. I really find that Malwarebytes and Superantispyware, along with your regular antivirus really does the trick most of the time.
Others that I have used are Hijack This, Combo Fix, Hitman Pro.
I aso like to use Virustotal if I know what the troubled file is and see who has virus def for it.