if you mean work on both by lots of registry tweaks and customization
but a month in on a laptop using 8 as it is meant to be and no- it is keyboard and mouse compatible - not the same as native. what they have is a tablet and phone front end they are shoehorning onto the desktop. And the horizontal scrolling for the start menu!
whoopee - apps on the desktop- not big for the enterprise or home users.
I expect it will come to a separate build to the desktop with the ability to still transport to the tablet and phone- but I don't see this as One OS To Rule Them All.....