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What do the various creators of the testing software listed above have to gain by falsifying results? How could they all get together and falsly show there was no performance increase? Why would Symantec or other unnamed "big corps" be interested in paying them to hide performance benefits of registry cleaners? Wouldn't the "big corps" be more interested in trying to sell cleaners of their own... if they actually worked?

Solution: run your own tests.

If conspiracy theories keep you from trusting results from any of the above, download the open source Phoronix Test Suite, go over the code yourself, compile it, and use that. Results will still be the same: "cleaning" of registry results in no measurable speed increase.