Bloatware
Luckily my organization is fairly small (100 users ). With only two in I.T. bloatware is a real problem with OEM's. Unfortunately many of our PC's are different models as we buy them in chunks or we'd just wipe and install one models with the proper software and none of the bloat and image that box. We've tried solutions like CCleaner and it has caused other problems for us (HIPPA, NISH certifications) so we do it the old fashioned way, manually!