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Overall slower system
In most cases if you are still using a mechanical drive, compression will slow the system down and may not even do much for helping with any kind of space issues unless the files are primarily uncompressed data files. Many programs are already compressing their data files and you won't see much improvement because of that. Images (.jpg, etc) will have very poor compression ratios and may actually end up larger than the original. Executables normally do not achieve good compression ratios either. So if this is a system with a single hard drive, your gains will most likely be miniscule if you see any benefits at all.