high speed travel in the wrong direction
The problem is that the specific path down which some frameworks direct developers is often the wrong direction -- sometimes subtly, sometimes less so, but those who are not as familiar with the wide world of alternatives may not realize there's another way to do things. It becomes one's hammer, and every problem becomes a nail, even if it's shaped more like double-sided tape or a Faberge egg.
Basically the only thing for which Qt is actually suited is KDE desktop applications.