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One that (surprisingly) didn't make the list
Have learned many, many things by reading Brien Posey's works, but I think a program I've relied upon (in one v. or another) since 2002 should have made this list; I find it especially useful when used to create before & after snapshots during the installation of new software. The program is AShampoo's UnInstaller 4; it contains many other useful tools & features, including a fairly comprehensive suite of file & folder deletion/cleaning tools, a utility for "undeleting" files, a "behind-the-senes" real-time defragmenter with a companion boot-time defragger for system files like the page file, a real-time Installation Monitor, the ability to manage fonts, Windows Services (ala Sysinternal's Autoruns, but perhaps even MORE facile), IE Add-ons, and System Restore points (going CCleaner one better, it allows the deletion of ANY SysRestorePt, including the latest one). The Registry Cleaner facilities are pretty useful as well. There's more, but this comment is large enough w/o going into more detail, and AShampoo's available documentation is extensive. One of the features many users may like best is the very reasonable price for the full-featured v. of Uninstaller, for AShampoo is famously flexible about pricing. Also, they'll even sell you multiple-year warranty & support that really works, again @ a pretty-reasonable price. The company WILL try and sell you more of their useful products (I'm also a fan of their CAD software), but they don't inundate you with emails and popups as do so many progams these days.