as well as full blown virtual machines.

Cedega is a commercial program aimed at games and is a step ahead of WINE as it's the same bunch of people working on it and how they put food on the table.

I use Zorin OS 5 which works off the Ubuntu base with a few extras added, like a big range of GUIs that imitate other systems, and it has a program called Play on Linux (which may be in the Ubuntu repository) to help run Windows programs.