TNT is right!...
Although I haven't tested Threatfire, I recommend it and the Defense+ portion of Comodo which is constantly improving. You only need the firewall for this, but I can't attest to the full suite.
As I posted in your last article(I think); Emisoft's Mamutu already has a reputation for foiling the German government's spyware. At least this puts it in the news. I was impressed with the ability of Mamutu to find all of my hidden DRM spys in 5 seconds, after installation!!! I was never able to find them before, so that I could tech problems with protected content under IAA rules.
Unfortunately it is a paid solution, so I recommend a combo of Winpatrol, Comodo firewall with Defense+, and Threatfire. Even if you get into a fight with some really heavy hitters, with these solutions, and lose your computer, you will at least foil the mission of the criminals. I must say though, that the small number of clients I have, who are targets of government, or international industrial espionage, have had to give up on their PCs. The only next step for many of them is to graduate to high assurance hardware/software; and this is prohibitive in cost to many of them. One of them is luckily getting by with an old Mac using RISC (or the old Motorola) CPU architecture. Apparently they haven't been coding for that yet. There is also the solutions that operate in an infected enviroment, like Keyscrambler, Rapport, and LastPass. We need more thinking along these lines, if we are ever going to get a handle on this!
And there is always the LiveCD Puppy Linux solution - preferably run from an old PC with no firmware in the DVD device, and a fresh reflashed bios - no PCI cards. Doesn't hurt to keep this PC totally isolated inside the LAN with a KVM switch.
Bear in mind, that these attackers are so sophisticated that they have no trouble using your cell phone as a skip pad to attack your LAN and PC devices. One client I knew lost his Mac(intel based) during this kind of assault!