I stumbled upon this company called unitrends while on spiceworks a few months ago, and they actually have some of their enterprise backup software for free. Granted, it can only backup VM's, but I have a total virtual datacenter here, so as a proactive measure this is perfect. =P

On the reactive side of things Hiren Boot CD has been my fav since high school and it still is now, especially when I get lazy with finding passwords lol.

And in terms of general security, for personal and work use, MS Security Essentials has been FANTASTIC in terms of AV/Firewall protection.

These three make my life soooo much easier.