the latest versions...
the most recent version - you CAN'T just start in safe mode. You can only use safe mode with command prompt, then use Windows Key + E to open explorer, then plug in a USB with some "stand alone" and Portable antivirus, and Anti malware and Trojan killers - copy them all to the HDD and try to run them from there.
Your installed Antivirus will be useless until this gremlin is killed.
I just had to remove one of these nasties about 6 weeks ago from a friends computer - had to battle it for a couple of days - not a simple fly-swatter job.
Deleting certain folders and or files can also be locked out as you may find your ADMIN privileges are revoked - you may be able to install IOBits Windows Unlocker ...
MajorGeeks site is a good resource to locate a load of tools and virus killers etc..
