Many, many years ago I was an admin for a niche computer/operating system. One of the users went off his meds shortly after I upgraded the OS. I explained what changes he'd have to make to his code to keep it working and he wasn't too happy. Coworkers would smile as they came to 'check on me'. A couple weeks and incidents later (fortunately not w/me) he was on indefinite medical.

Now that I think of it, how many of us could use the meds excuse if Windows 8 was forced upon us at work