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Printers are bad enough, but usually I can find a pilot to install one, but scanners are something else. The very thought of Twain almost gives me nightmares. How many customers have a scanner that they don't use very often - "its almost new, it can be obsolete!!" but for which we can never find a pilot to make them work on Vista or 7- especially on 64bit.
Alternatively they use it all the time and can't be without it, and they don't want to change because it works just the way they want, they know how to do what they need.