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Apart from the user interface (get classic shell from Sourceforge - this makes it look like Windows 7) and things like Hyper-V, it really isn't that much different from Windows 7.

Any incopmatibility problems (unless you are running Windows RT which is completely different) are most likely to be down to an old program doing something insecurely. Unfortunately, that is the price of progress - at times developers have to draw a line and say that doing things in the same way hampers progress too much.