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For myself, I find Karen's Backup to be great. It has incremental and differential as well as a lot of settings to fine tune your backups and your target. You can also backup just one file, a single directory or part of the HDD. It does not have encryption though, so there is no security. But I have several backups scheduled every night. Things like key work files to a USB that goes with me every day so I can take my work from the previous evening with me, to sending files to the cloud and my external HDD for dual backups. I also do a full backup weekly. Great tool! And it is free!