Spybot Search & Destroy (also FREE) by Safer Networking make a perfect duo! Just make sure SbS&D's "Resident 'Tea Timer'" is on.
They both UNinstall quite cleanly.
I've use these two programs together for over five years and have found them to be extremely reliable. My computer(s) haven't been infected with anything without me
knowing it and giving me the chance to take care of it
IMMEDIATELY before losing data. And that has only happened a
very small of times. But, I'm a home user. I also practice "safe surfing" techniques, never use Outlook for mail and don't open ANYthing from someone I don't know (
even through Y!).