New Hard Drive--Partition or not?

Of course, you need to create at least a single partition in order to use your drive.

I believe the Vista installer still allows you to create a boot partition of the size you desire, and then partition the rest of the drive later.

I myself like to use multiple logical drives.

That way, I can store my data files separate from my OS and can easily back up just my files.

Here is a good article on the ins and outs of multiple partitions:

http://www.aumha.org/a/parts.htm

Chas