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Can someone help - PS2 Mouse doesnt work in combination with USB Keyboard?

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Can someone help - PS2 Mouse doesnt work in combination with USB Keyboard?

IrishAL0
Hello, firstly I have tried to search for a solution to this problem using Google & the search facility on the discussion page but with no success so I hope someone can help.
I recently purchased a new Dell USB keyboard for my desktop PC. Previously I had a PS/2 keyboard and still use a PS/2 mouse. The problem is that the new USB keyboard works fine but the PS/2 mouse has stopped responding (power LED is on). I restarted the PC with old PS/2 keyboard plugged in again & new USB keyboard also plugged in and this time the mouse worked again, then I unplugged the PS/2 keyboard and mouse still worked, restarted the PC and again the mouse had stopped working.

I'm running Vista.

Help!

Regards
Alan .