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Cisco Pix 506e firewall blocking Win07 from accessing a specific website?

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How about adding a host file entry for your website directly on the win 07 machine?
go to the c:\windows\system32\drivers\etc and edit the hosts file using notepad.
Leave everything in the file and at the bottom, after the ## comments, add the ip address and hostname of the server exactly as it would resolve on the internet and exactly as the remarks show it. dont add number symbol to your line. This will bypass dns for the web site.
If this works, it will buy you some time to look into the dns and pix issues. These 07 machines have the windows firewall turned on or off? If on, you can try switching that off as well, to rule it out.

I'm still confused with the dns part of this. I assume you have internal dns servers (maybe not) and they should use external helpers. When you did your ipconfig /all are you getting internal or external dns server ip addresses?