+ 0 Votes username = "guest" ? Absolutely Updated - 6 years ago Sorry, I just have no idea why that would happen, unless she likes you and is just intentionally locking the file as an excuse to call you for "technical support". + 0 Votes ok, test the theory......... ThumbsUp2 6 years ago Move the file to a different location on the server, test it, then try moving that file to her computer and open it directly, test it, then create a shortcut to the file on her computer, test it..... Test all ways possible to open that one file. + 0 Votes Can she access the file from a different system? LocoLobo 6 years ago Have you had her log into her system then tried launching the shortcut yourself to see what is happening? I don't have any idea what it could be either, just grasping at straws. + 0 Votes Corrupt shortcut? Try this......... ThumbsUp2 6 years ago When this issue starts happening, have her start Excel first, close the new workbook, then do file/open and navigate to where the file in question is located. See if it will open that way. If it does, the shortcut has become corrupt, possibly even trying to open the file with certain flags set or from a share/domain location that wasn't closed properly. + 0 Votes have you uninstalled and reinstalled excel on her system? LocoLobo 6 years ago Just a thought. Could it be the HW itself? My work place has some older PCs that "act up" when using excel sometimes. But it's not one person/one file it seems to be more random. + 0 Votes Check mapped drives....... ThumbsUp2 6 years ago There's an article at MS that says if you try to open a file that's on a mapped drive and the program hangs, check all mapped drives. If one is not responding or temorarily disconnected, the application will hang. http://support.microsoft.com/kb/313937/en-us WORKAROUND To work around this behavior, use one of the following methods. Method 1: Do not use persistent connections When you connect a mapped drive, click to clear the Reconnect at logon check box. By clearing this check box, the mapped drive will not be connected the next time that you log on to the computer. See the "More Information" section for more information about how to map a network drive. Method 2: Use a user logon script If you can, use a logon script to connect a user to the appropriate servers every time that the user logs on. Make sure that the script maps the drive in a non persistent state. If the drive is not available as the logon script runs, the drive is not mapped. This behavior prevents the issue. Method 3: Use server mirroring If the connection is over a Wide Area Network (WAN), consider implementing server mirroring. Server mirroring duplicates a distant server locally. Then, map your drive to the local, duplicate server. Doing this can reduce the wait time by connecting to a local server. Method 4: Use a shortcut to the network location Use a shortcut on the Microsoft Windows desktop or in My Network Places to connect to the network location that you want.