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is it safe to delete 1 pagefile.sys if you have 2 internal HD's?

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should be, as long as you make sure Windows has actually reconfigured properly to use your other drive and turned it off on C:\...doesn't sound as though yours has
However - I have tried this several times and frankly it makes no discernible difference whatever and it can lead to problems if your other drive becomes unavailable.
Also if you have a faster disk why not put Windows on it and use the slow disk for data or whatever?