+ 0 Votes IP of Exchange Server retro77 6 years ago Did the IP address of the exchange server or the name change? If the name changed, then the profiles have to be recreated. There are software solutions out there, but it seems you ahve to buy them. + 0 Votes have you tried what in these MS KB articles CG IT 6 years ago http://support.microsoft.com/kb/870926/ the other place to go is Exchangeserver.org http://www.msexchange.org/ + 0 Votes Test it retro77 6 years ago If you delete an Outlook profile, does this delete the offline mail? Even if it does, when you recreate the profile, you'll be in cached mode and it will download your mailbox again. Or: set it up to not be in cached mode and once the sales person gets back to the office, set them up as cached. But definately your going to have to recreate the Outlook profiles if the server is new, even with the same name and IP. DHCP: it wouldnt be a DHCP issue since you can connect to resources. + 0 Votes Same Issue steve.schwindt 6 years ago I have the same exact issue on my network. My VPN users can access all resources except exchange. Some had stated in a reply that if you can connect to the VPN then the problem is not with ISA. Actually, what I did was install outlook on the ISA server and tryied to connect to exchange from it and got the same exact symtom, and when I stopped the firewall service on ISA it worked fine, plus the fact that I connected to a RRAS, (non-ISA), server on the same LAN as ISA from the same remote laptop and I could access exchange just fine, so the the problem is in fact with ISA, I just can't find where.