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Question about Certain folders and Files

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OH Smeg

You should leave the Install Folder in Windows alone though it will not cause the system to BSOD but it may very well prevent software loading by removing files from that folder.

As for a piece of Software to delete unnecessary folders or files there is nothing I would trust not to cause more problems than they fix.

Not really sure why you want to delete these files anyway but if you must then look at the Uninstall Files in the Windows Folder though that will most likely prevent you removing installed software and the Temp Folder in the Windows Folder which can be emptied fairly safely.