Very complicated USB HDD Problem....

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Very complicated USB HDD Problem....

Hey there,

I have a 250GB external hard drive (in an enclosure) for my Compaq Presario V6000 laptop which is running Windows Vista home. Although Vista detects and installs drivers for the hard drive..the drive does not appear in 'Computer'. I go to 'Disk Management' and I am unable to intialise or format the drive. The drive appears as unreadable and unallocated and unknown. I right click on the unallocated area and I dont get any other clickable options other than properties or help. The 'New Simple Volume' option is unclickable.

Can anyone help me fix this problem?

I managed to get one step further I think... and managed to get Vista to think it could inititialize the disk.. but then received another Error.
Unexpected failure. Error code: 45D@0200001A
I'm am demented! The drive worked fine a couple of days ago. I have yet to find anyone with a solution to this...

Thank you for any help offered!
Additional details: It is not a power supply/cable problem. It is not a disk letter allocation problem - that used to be fine at G:/ - I am now unable to allocate a letter. I have been unable to use data recovery software as they won't work on a disk my OS doesn't recognise.
Thanks again...