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What are the trade-offs in upgrading from MS Office 2003 to 2010?

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I've been using the 2010 beta since it was released (on Vista Business SP2).

Your PC is well above the minimum hardware requirements published by MS (granted, they are absurdly unusably low minimums)

- App load times seem slightly slower
- In the apps response time is about equivalent for me
- your machine should be adequate to running 2010
- I haven't noticed any significant impact on other apps
- 2010 Ribbon is more customizable than 2007 (which was effectively locked unless you wish to edit XML code), but still no where near as customizable as the 2003 menus (you may import customized menus into 2010)
- Some of the graphical tools like Wordart and charts provide different options. Generally new ones are added, but a few are lost. You can "recover" these "missing" functions by opening a 2007 or 2003 formatted file in "compatibility mode"