A General Model for Amino Acid Interaction Networks

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Executive Summary

In this paper the authors introduce the notion of interaction network of amino acids of a protein (SSE-IN) and study some of the properties of these networks. The main advantage of this model is that it allows to cope with different biological problems related to protein structure using graph theory tools. Ignoring details, such as the type and the exact position of each amino acid, this paper and compact description allows to focus on the interactions' structure and organization. They have shown that the subnetworks corresponding to secondary structure elements satisfy the properties of the small-world network model. Small-world networks are widely studied and their properties are well identified. These properties can give insight on the formation of SSEs.

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