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In this paper, the asymptotic Signal-to-Interferenceplus-Noise Ratio (SINR) performance of Multi-Carrier Direct-Sequence Code-Division Multiple-Access systems employing Time-Frequency-Domain Spreading, i.e., of the TF/MC DS-CDMA systems, is studied, when separate Minimum Mean-Square Error Multi-User Detection (MMSE-MUD) is considered. The separate MMSE-MUD detects signals first in the Time (T)-domain and then in the Frequency (F)-domain. Based on random matrix theory, closed-form expressions for the asymptotic SINR of the TF/MC DS-CDMA systems using separate MMSE-MUD is derived, when communicating over Additive White Gaussian Noise (AWGN) channels. The closed-form expressions show that the asymptotic SINR performance is only depended on the T- and F-domain user load factors as well as noise variance.
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