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The amount of biological data publicly available has experienced an exponential growth as the technology advances. Online databases are now playing an important role as information repositories as well as easily accessible platforms for researchers to communicate and contribute. Recent research projects in image bioinformatics produce a number of databases of images, which visualize the spatial expression pattern of a gene and most of which also have one or several annotation keywords. C-DEM is an online system for Drosophila (= fruit-fly) Embryo images Mining. It supports queries from all three modalities to all three, namely: Genes, images of gene expression, and annotation keywords of the images.
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