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This paper studies Interference Alignment (IA) based multi-cell cooperative resource allocation for the downlink OFDMA with universal frequency reuse. Unlike the traditional scheme that treats subcarriers as separate dimensions for resource allocation, the IA technique is utilized to enable frequency-domain pre-coding over parallel subcarriers. In this paper, the joint optimization of frequency-domain pre-coding via IA, subcarrier user selection and power allocation is investigated for a cooperative three-cell OFDMA system to maximize the downlink throughput. Numerical results for a simplified symmetric channel setup reveal that the IA-based scheme achieves notable throughput gains over the traditional scheme only when the inter-cell interference link has a comparable strength as the direct link, and the receiver SNR is sufficiently large.
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