Business Intelligence

Greedy Search-Binary PSO Hybrid for Biclustering Gene Expression Data

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Executive Summary

As a useful data mining technique biclustering identifies local patterns from gene expression data. A bicluster of a gene expression dataset is a subset of genes which exhibit similar expression patterns along a subset of conditions. In this paper a new method is introduced based on greedy search algorithm combined with the evolutionary technique particle swarm optimization for the identification of biclusters. Greedy methods have the possibility of getting trapped in local minima. Metaheuristic methods like particle swarm optimization have features for escaping from local minima and can find global optimal solutions.

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