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Grid computing has gone through some generations and as a result only a few widely used middleware architectures remain. The Globus Toolkit is the most widespread middleware in most of the current production grid systems, but the LCG-2 middleware dominates in Europe. In this paper, the authors present a brokering solution that enables the interoperability of various Globus and LCG-2 based grids during the execution of work flow applications, and supports users to utilize computing and storage resources from multiple production grids by a single application. The development and execution of such applications can be managed by a Web-based Grid portal called P-GRADE Portal, and the brokering of the work flows is carried out by its integrated GTbroker and LCG-2 broker component.
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