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This paper proposes practical methods for and examines the benefit of dynamic power spectrum optimization for interference mitigation in wireless networks. The paper envisions a distributed antenna system, deployed as a means to increase the network capacity for areas with high data traffic demand. The network comprises several Access Nodes (AN), each serving a fixed set of remote radio units called Remote Terminals (RT). The RTs belonging to each AN are separated from each other using Orthogonal Frequency Division Multiple Access (OFDMA) over a fixed bandwidth, where only one RT is active at each frequency tone.
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