Genbit Compress Tool(GBC): A Java-Based Tool to Compress DNA Sequences and Compute Compression Ratio(bits/base) of Genomes

Source: Cornell University

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The authors present a Compression Tool, GenBit Compress', for genetic sequences based on their new proposed "GenBit Compress Algorithm". Their Tool achieves the best compression ratios for Entire Genome (DNA sequences). Significantly better compression results show that GenBit compress algorithm is the best among the remaining Genome compression algorithms for non-repetitive DNA sequences in Genomes. The standard Compression algorithms such as gzip or compress cannot compress DNA sequences but only expand them in size. In this paper, they consider the problem of DNA compression. It is well known that one of the main features of DNA Sequences is that they contain substrings which are duplicated except for a few random Mutations.
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Date:Jun 2010