A novel coupled-fed antenna with compact branch-structure for 4G mobile phone is proposed in this paper. In the proposed design, a driven monopole strip and coupled branch-strips are developed to produce different operation band. The prototype of the proposed antenna was fabricated, tested and discussed. Simulation and measurement results reveal that the proposed antenna can provide two wide frequency bands (698-960MHz and 1710-2690MHz), which covers multi-band for LTE 700/GSM850/GSM900/DCS1800/PCS1900/UMTS/LTE2300/LTE2500. The proposed antenna with compact size of 34x12x6.5mm3 is suitable for today's mobile phone application.