In Of late due to excessive accumulation of genetic sequences need of vacuuming plays predominant role in database when it reaches to its threshold. Vacuuming refers to data should not be deleted physically but it is superseded. The achieved data can be stored in secondary storage, the authors can access it by writing temporal quarries but applying temporal quarries to genome data is spiky process. Hence need of zipping arises for processing, storing and managing data in a centralized and distributed environment. The genome is living organism encoded in DNA and RNA .Many existing algorithms had an eye on genome compression but they are having their own tradeoff in their compression ratios.