Relay selection in co-operative networks plays a vital role in increasing the efficiency of networks. If the selected relay is not the best relay then the end-to-end co-operative network will be in failure. In this proposed relay selection scheme, threshold-based relay selection is applied in the first-hop the source-to-relay link. From the destination, the best relay will be selected based on Output Threshold Multiple Relay Selection (OT-MRS) scheme. If the relay selected by the source and destinations are different then multi-relay transmission will take place between the relays.