Extensive research has been done on e-Commerce to demonstrate the tremendous benefits it offer Businesses. However, SMEs especially in developing countries have not fully adopted e-Commerce solutions. Therefore there is the need to identify and measure the perceived importance of driving forces and barriers in the adoption of e-Commerce solutions among SMEs. A questionnaire based on the factors identified has been developed and face-to-face interviews were conducted with 15 SME Managers which were inclusive of survey sample of 61 Ghanaian SMEs. This paper shows that SMEs online sales is virtually nil, the most common e-Commerce application is the use of e-mail for communication and the main reason for having a website is to show basic information about product and services as well as contact information.