The interest of physiological data sensing and recording using wireless body sensor network has increased in recent years due to the advancement of miniature and portable electronic devices. In this paper, the design of a portable and rechargeable data logger with high data rate multiple wireless connectivity (Bluetooth and 2.4-GHz radio frequency) is discussed. The data are logged in micro Secure Digital (SD) cards and can be transferred to PC or Smartphone using SD card reader, USB interface, or Bluetooth wireless link. Analog signals can also be logged through an 8-channel analog-to-digital interface. A graphical LCD with touch screen is added for control and diagnosis. The hardware is generic and targeted for various medical imaging and data collection applications.