With the development of hardware and software, GPU has been used in General-Purpose computation field. The high density of computing resource on chip brings in high performance as well as high power consumption. So the power consumption of GPU has increasingly become one of the most important issue for the development of general computing with GPUs. However, few research focus on estimating the energy consumption of GPU during the computing process. The goal of this paper is to build energy consumption model that can predict the energy consumed in the computing phase for various GPUs applications.